The kinetics of glutamate release allows proper transfer of sound information to the primary afferent auditory neurons. Supplement to otogelin, otogelinlike, and stereocilin. A free powerpoint ppt presentation displayed as a flash slide show on id. Myosin vi is required for the proper maturation and function of inner hair cell ribbon synapses. Cochlear inner hair cells ihcs, the mammalian auditory sensory cells, encode acoustic signals with high fidelity by graded variations of their membrane potential trigger rapid and sustained vesicle exocytosis at their ribbon synapses. Otogelin, otogelinlike, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.
A predicted structures of the yeast twohybrid y2h myosin viia bait mythy4ferm and spectrin. How the genetics of deafness illuminates auditory physiology. Pdf anatomie et physiologie du systeme vestibulaire. En important safety information 2 putting on powerbeats 5. Otoancorin knockout mice reveal inertia is the force for. Precisdephysiologiedelexercicelq532062020 adobe acrobat reader dcdownload adobe acrobat reader dc ebook pdf. With acrobat reader dc you can do more than just open and view pdf files its easy to add annotations to documents using a complete set of commenting tools. The study identifies clrn2 as a new deafness gene required for maintenance of transducing stereocilia in the sensory cochlear hair cells. This finding is remarkable because the tectorial membrane tm, although remaining functionally attached to the outer hair cell bundles, is completely detached from the spiral limbus.
Kros, christine petit, saaid safieddine, myosin vi is required for the proper maturation. Echelle logarithmique alexander graham bell, 18471922. Audition physiologie ipoacusia italien related to this theme 12 resources in data. A partir des recepteurs sensoriels, constitues des. Hypervulnerability to sound exposure through impaired.